Case reports

3D bioprinting skin

N Naidoo, W G Kleintjes, E P Kotzee, A Mukendwa, E Blecha, D Vythilingham, M Ponto

Abstract


We used adipocyte-derived stem cells in combination with previously used methods (platelet-rich plasma and cell seeding) to create a 3D bioprint of skin on a hydrophobic matrix dressing. The patient was a 16-year-old girl with 65% total body surface area burns who had had multiple previous operations, and required additional skin with minimal donor sites. The patient had a Pseudomonas aeruginosa wound infection that compromised graft take. The overall graft take at 2 weeks was between 20 and 60%. The results were satisfactory in this patient, but there is plenty of room for improvement to achieve 100% graft take. Further technical refinements in the technique and postoperative management could improve results.


Authors' affiliations

N Naidoo, Department of Surgery, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

W G Kleintjes, Western Cape Provincial Tertiary Adult Burn Unit, Division of Surgery, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa

E P Kotzee, Western Cape Provincial Tertiary Adult Burn Unit, Division of Surgery, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa

A Mukendwa, Western Cape Provincial Tertiary Adult Burn Unit, Division of Surgery, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa

E Blecha, Western Cape Provincial Tertiary Adult Burn Unit, Division of Surgery, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa

D Vythilingham, Western Cape Provincial Tertiary Adult Burn Unit, Division of Surgery, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa

M Ponto, Western Cape Provincial Tertiary Adult Burn Unit, Division of Surgery, Tygerberg Hospital and Stellenbosch University, Cape Town, South Africa

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Cite this article

South African Journal of Plastic & Reconstructive Aesthetic Surgery & Burns 2019;2(2):46-48. DOI:10.7196/SAJPRASB.2019.v2i2.20

Article History

Date submitted: 2019-10-15
Date published: 2019-10-15

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